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Unlock the IQIRVO (elafibranor) effect

Primary Biliary Cholangitis (PBC) Video
02:17

For healthcare professionals caring for people prescribed IQIRVO.

Abbreviations
PPAR, peroxisome proliferator-activated receptor; UDCA, ursodeoxycholic acid.

Footnote
*IQIRVO + UDCA met the primary endpoint of cholestasis response, defined as by ALP <1.67 x ULN, and ALP decrease ≥15% and TB ≤ULN. Reduction in ALP and bilirubin is predictive of long-term outcomes.1–5

References

  1. IQIRVO® (elafibranor) Summary of product characteristics (SmPC). 2024
  2. Lammers WJ et al. Gastroenterology. 2014;147(6):1338–1349.
  3. Corpechot C et al. Clin Res Hepatol Gastroenterol. 2022;46(1):101770.
  4. de Veer RC et al. Aliment Pharmacol Ther. 2022;56(9):1408–1418.
  5. Murillo Perez CF et al. Am J Gastroenterol. 2020;115(7):1066–1074.

IQV-UK-000155 | January 2025

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This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get. Reporting of side effects. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in Google Play or Apple App Store. Side effects should also be reported to Ipsen via email at pharmacovigilance.uk-ie@ipsen.com or phone 01753 627777. By reporting side effects, you can help provide more information on the safety of this medicine.